We present a series of simple, largely analytical models to compute the eff
ects of disruption on the mass function of star clusters. Our calculations
include evaporation by two-body relaxation and gravitational shocks and mas
s loss by stellar evolution. We find that, for a wide variety of initial co
nditions, the mass function develops a turnover or peak and that, after 12
Gyr, this is remarkably close to the observed peak for globular clusters, a
t M-p approximate to 2 x 10(5) M-circle dot. Below the peak, the evolution
is dominated by two-body relaxation, and the mass function always develops
a tail of the form psi (M) = const, reflecting that the masses of tidally l
imited clusters decrease linearly with time just before they are destroyed.
This also agrees well with the empirical mass function of globular cluster
s in the Milky Way. Above the peak, the evolution is dominated by stellar e
volution at early times and by gravitational shocks at late times. These pr
ocesses shift the mass function to lower masses, while nearly preserving it
s shape. The radial variation of the mass function within a galaxy depends
on the initial position-velocity distribution of the clusters. We find that
some radial anisotropy in the initial velocity distribution, especially wh
en this increases outward, is needed to account for the observed near-unifo
rmity of the mass functions of globular clusters. This may be consistent wi
th the observed near-isotropy of the present velocity distributions, becaus
e clusters on elongated orbits are preferentially destroyed. These results
are based on models with static, spherical galactic potentials. We point ou
t that there would be even more radial mixing of the orbits and hence more
uniformity of the mass function if the galactic potentials were time-depend
ent and/or nonspherical.