Temporal organization is a fundamental feature of all living systems. Timin
g is essential for development. growth and differentiation and in the matur
e organism, it is essential to maintain normal physiology and behavior. The
biological entity that permits an organism's day/night organization is the
circadian system. In the following, we describe how daily or circadian act
ivity is measured in mice, and what such activity measurements can tell us
about the state of the animal. (C) 2001 Elsevier Science B.V. All rights re
served.