Survival of women with breast cancer in France: variation with age, stage and treatment

Citation
P. Grosclaude et al., Survival of women with breast cancer in France: variation with age, stage and treatment, BREAST CANC, 70(2), 2001, pp. 137-143
Citations number
14
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BREAST CANCER RESEARCH AND TREATMENT
ISSN journal
01676806 → ACNP
Volume
70
Issue
2
Year of publication
2001
Pages
137 - 143
Database
ISI
SICI code
0167-6806(2001)70:2<137:SOWWBC>2.0.ZU;2-G
Abstract
This study examines survival of women with breast cancer using a sample of 1564 cases occurring in 1990 taken from all cases recorded in seven French cancer registries. Age at diagnosis pathological stage (pTNM) and treatment were the criteria selected for the study of the survival. We studied the 5 -year observed survival and the relative survival. Tumors pT1 represented 4 6.7% cases, pT2: 31.6%, pT3 and pT4: 9.2%, and 52% of the tumors had no nod al involvement or metastasis. For cases without surgical treatment the prog nosis was poor (observed survival 18.7%, relative survival 25.9%). For wome n benefiting from neoadjuvant treatment, observed survival rate was 65% aft er 5 years and relative survival rate 69.1%. For women who were treated fir st with surgery, the observed survival was 79.5% and the relative survival 86.7%. The survival rate for women under 40 years was slightly lower than f or the 40-54-year-old. Using relative survival the youngest group had the w orst prognosis and the oldest group the best. In older women, therapeutic s trategy might have been more selective which leads to a better prognosis th an in the younger age groups treated in a comparable way.