The cataractogenic effects of the microwave oven on rat eyes were inve
stigated histologically. Twenty-one adult Wistar-Albino rats (2-2.5 mo
nths old) were divided into three groups (n = 7): a control group (sha
m-exposed) and two experimental groups. The experimental rats were con
fined in special cages and placed next to the closed door of a microwa
ve oven. The first experimental group was given 15 minutes of daily ex
posure and the second. 30 minutes, for 1 month. Biomicroscopic examina
tion detected no pathological damage to the lens in the experimental r
ats. Histologically, there was a lens of single-layered epithelium in
the control group. Tn the first experimental group. there was slight p
leomorphism in the superficial epithelial cell contours and vacuolizat
ions in the lens fibers: the second experimental group, had pronounced
pleomorphism and pyknosis of the nuclei in the superficial epithelium
. Some of the superficial epithelial cells had disappeared and were hi
stologically observed as acellular areas, Single-layered epithelium be
came disorganized and formed multilayered epithelial groups in the sup
erficial epithelium. Vacuolization was more prominent in this group. P
ersonal exposure from microwave ovens is generally minimal because of
the rapid decrease in power density with distance. Microwave oven user
s do not normally stand as close to the oven as the rats in our study
were placed: therefore, it is difficult to suggest that microwave oven
s always have cataractogenic effects on human eyes. (C) 1997 Japanese
Ophthalmological Society.