Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate

Authors
Chowdhury, MMU Motley, RJ
Citation
Mmu. Chowdhury et Rj. Motley, Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate, CLIN EXP D, 26(8), 2001, pp. 657-660
Citations number
12
Categorie Soggetti
Dermatology
Journal title
CLINICAL AND EXPERIMENTAL DERMATOLOGY
ISSN journal
03076938 → ACNP
Volume
26
Issue
8
Year of publication
2001
Pages
657 - 660
Database
ISI
SICI code
0307-6938(200111)26:8<657:TOACOH>2.0.ZU;2-8
Abstract
A 71-year-old man with acrodermatitis continua of Hallopeau was treated suc cessfully with a combination of oral propylthiouracil and methotrexate. Aft er 14 weeks, he developed acute pancytopenia, an uncommon idiosyncratic sid e-effect of propylthiouracil, and presented with a life-threatening methici llin-resistant Staphylococcus aureus pneumonia. This illustrates the potent ial value and associated risks of propylthiouracil in the management of thi s difficult condition.