Unusual etiology of visual loss in an HIV-infected patient due to endogenous endophthalmitis

Disseminated candidiasis, especially ocular infections such as endophthalmi tis, is uncommon in HIV-infected patients. We report a case of candidal end ophthalmitis in an HIV-positive non-drug-user patient, following candidemia from a cutaneous abscess at the site of a peripheral catheter. Ocular dise ase was revealed by a visual decrease in the left eve. DNA analysis using R -APD showed identical patterns of Candida albicans isolated from the skin a nd eye. Combination therapy with high-dose fluconazole and intravenous amph otericin B was performed. Two intravitreal amphotericin B injections and a vitrectomy were administered because of an amblyopic right eye and severe v itritis. The outcome was favorable without relapse at 18 months.