Herbal medicinal use has increased dramatically in recent years. The increa
sing use of these products is of concern, and their use may not be recogniz
ed by the treating physicians. Many of these remedies have potential for ad
verse interactions with medications commonly prescribed for various cardiov
ascular disorders. Despite their widespread use, limited data exists regard
ing the efficacy of herbs such as echinacea, garlic, ginseng, gingko, ephed
ra, and St. John's wort. Of special concern is the ability of herbal remedi
es to potentiate effects of prescription drugs with a narrow margin of safe
ty. An increasing awareness of the potential for harmful effects of herbal
remedies has given the impetus for aggressive interventions to inquire abou
t the use of these agents and systematic reporting of adverse events emanat
ing from their use. This review briefly summarizes important adverse intera
ctions of commonly used herbal remedies with prescription cardiovascular me
dications. Coronary Artery Dis 12:581-584 (C) 2001 Lippincott Williams & Wi
lkins.