Objectives: The aim of this study was to investigate and evaluate the presc
ribing habits of family pediatricians in Southern Italy in order to determi
ne which aspects need to be addressed for a more rational use of drugs in c
hildren.
Methods: An observational prospective study was conducted for a 3-month per
iod in 1998 in which family pediatricians were asked to record information
regarding every patient-doctor contact on an index day of the week. The inf
ormation was collected on a specifically designed data collection form and
included the reason for the contact, the child's general characteristics, t
he drugs prescribed, and the purpose for which they were prescribed (therap
eutic indication). The data were entered, prescribed drugs were classified
according to the International Anatomic-Therapeutic-Chemical Classification
system (ATC), and the therapeutic indications were coded using the Interna
tional Classification of Diseases (ICD-9). Analyses were carried out using
the EPI-Info software package and the SPSS statistical analysis program.
Results: A total of 35 pediatricians participated and consulted with 9917 c
hildren, prescribing 8805 drugs to 6417 patients under 12 years old. Prescr
iption rates were higher for younger children. In all, 288 different generi
c substances were prescribed, but the 20 most common made up two-thirds of
the prescriptions and would have sufficed to cover almost 70% of all prescr
iption purposes. Two-thirds of prescriptions concerned respiratory system d
rugs or anti-infectives. Acute pharyngotonsillitis, cough, and acute otitis
media were the most common morbidities. Despite the free availability of d
rugs in the Italian health care system, the families paid for over half the
ir cost mainly due to the incorrect manner in which they were prescribed.
Conclusions: Although, according to current recommendations, most of the pa
tients' needs could have been taken care of using few drugs, prescriptions
involved a wide variety of compounds. Prescription practices did not follow
guidelines and were widely "evidence unbased". Prescribing drugs is one of
the most frequent interventions in general practice, yet more effort is ne
eded to establish a rational use of drugs in children, as well as in adults
.