Gene expression and fast construction of distributed evolutionary representation

Citation
H. Kargupta et Bh. Park, Gene expression and fast construction of distributed evolutionary representation, EVOL COMPUT, 9(1), 2001, pp. 43-69
Citations number
88
Categorie Soggetti
Computer Science & Engineering
Journal title
EVOLUTIONARY COMPUTATION
ISSN journal
10636560 → ACNP
Volume
9
Issue
1
Year of publication
2001
Pages
43 - 69
Database
ISI
SICI code
1063-6560(200121)9:1<43:GEAFCO>2.0.ZU;2-B
Abstract
The gene expression process in nature produces different proteins in differ ent cells from different portions of the DNA. Since proteins control almost every important activity in a living organism, at an abstract level, gene expression can be viewed as a process that evaluates the merit or "fitness" of the DNA. This distributed evaluation of the DNA would not be possible w ithout a decomposed representation of the fitness function defined over the DNAs. This paper argues that, unless the living body was provided with suc h a representation, we have every reason to believe that it must have an ef ficient mechanism to construct this distributed representation. This paper demonstrates Polynomial-time computability of such a representation by prop osing a class of efficient algorithms, The main contribution of this paper is two-fold. On the algorithmic side, it offers a way to scale up evolution ary search by detecting the underlying structure of the search space. On th e biological side, it proves that the distributed representation of the evo lutionary fitness function in gene expression can be computed in polynomial -time. It advances our understanding about the representation construction mi gene expression from the perspective of computing. It also presents expe rimental results supporting the theoretical performance of the proposed alg orithms.