Evaluation of LabChip (TM) technology for GMO analysis in food

Authors
Birch, L Archard, CL Parkes, HC McDowell, DG
Citation
L. Birch et al., Evaluation of LabChip (TM) technology for GMO analysis in food, FOOD CONTRO, 12(8), 2001, pp. 535-540
Citations number
14
Categorie Soggetti
Food Science/Nutrition
Journal title
FOOD CONTROL
ISSN journal
09567135 → ACNP
Volume
12
Issue
8
Year of publication
2001
Pages
535 - 540
Database
ISI
SICI code
0956-7135(200112)12:8<535:EOL(TF>2.0.ZU;2-G
Abstract
Ongoing technological advances permit the development of new scientific str ategies for bio-analysis. The work described here sought to compare a tradi tional agarose slab gel electrophoresis method combined with digital image analysis against a new microfluidic capillary electrophoresis system (LabCh ip (TM), Agilent Technologies) to assess their relative performance in the quantitative analysis of polymerase chain reaction (PCR) products. The comp arative strategy exploited methodology for providing quantitative genetical ly modified organism (GMO) determinations in food samples and demonstrated that the LabChip (TM) system offered improvements in quantitation accuracy, objectivity and ease of use. (C) 2001 LGC (Teddington) Ltd. Published by E lsevier Science Ltd. All rig ts reserved.