RENAL-TRANSPLANTATION IN CHILDREN FOLLOWING AUGMENTATION URETEROCYSTOPLASTY

Objectives. To assess the impact of augmentation ureterocystoplasty on the success of cadaveric renal transplantation in children with dysfu nctional bladders. Methods. Two patients with end-stage renal failure secondary to dysfunctional bladders (one myelodysplasia and one poster ior urethral valves) underwent augmentation ureterocystoplasty prior t o renal transplantation in order to increase bladder capacity and impr ove compliance. Results, Significant improvement of bladder storage fu nction was achieved in both patients. By the use of megaureter for aug mentation, untoward sequelae of enteric or gastric augmentation were o bviated. Renal transplantation was successful in both patients. Both h ave normal renal function 4 and 3 years after transplantation. Conclus ions. Renal transplantation into bladders previously augmented with me gaureters is successful. The use of urothelial-lined biomaterial for a ugmentation avoids the potential complications of gastro- or enterocys toplasty, which are especially dangerous in transplant patients. (C) 1 997, Elsevier Science Inc. All rights reserved.