Wk. Stadelmann et al., THE USE OF SELECTIVE LYMPHADENECTOMY IN SQUAMOUS-CELL CARCINOMA OF THE WRIST - A CASE-REPORT, The Journal of hand surgery, 22(4), 1997, pp. 726-731
Squamous cell carcinoma is the second most common skin cancer in human
s and has a rare of metastasis of 0.5%-5.9%. Regional lymphadenectomy
is generally not recommended for patients with advanced lesions and cl
inically node-negative disease. Selective lymphadenectomy using preope
rative lymphoscintigraphy and intraoperative radiolymphoscintigraphy a
nd vital dye injections to identify the sentinel lymph node may help i
n staging patients with upper-extremity squamous cell carcinoma while
avoiding the complications of a complete axillary node dissection. The
case of a patient with a large squamous cell carcinoma of the wrist w
ith clinically negative findings an axillary examination who was found
to have a sentinel lymph node containing metastatic tumor is presente
d. Although this treatment method is still considered investigational,
it holds great promise for nodal staging by being able to detect occu
lt metastatic nodal disease in otherwise clinically node-negative pati
ents.