Invasive pulmonary aspergillosis in a puerperant with drug-induced agranulocytosis

Invasive pulmonary aspergillosis (IPA) is an acute infection of Aspergillus species to the lungs. It generally occurs in immunocompromised hosts, espe cially with neutropenia. We report a 30-year-old puerperant, who developed IPA from agranulocytosis. She had been treated for threatened labor with ri todrine and cefepime, one of which induced agranulocytosis. After vaginal d elivery of twins, pneumonia emerged in the right lower lobe. She was diagno sed to have EPA according to the halo sign on computed tomography (CT) and positive circulating antibody against Aspergillus, and was treated successf ully with oral itraconazole followed by surgical resection. It is important to note that IPA might arise in otherwise immunocompetent hosts when neutr openia is long-standing.