A cross-sectional study of 28 patients with multiple congenital contra
ctures of miscellaneous origin is presented. We describe the clinical,
genetic, and neurological diagnosis and the involvement of upper and
lower extremities and spine. AU treatments that patients received so f
ar as well as functional outcome were studied. We compared these facto
rs in children with anterior horn cell degeneration (AHCD) or amyoplas
ia with those of children with contractures of other origin. A correct
genetical diagnosis of multiple congenital contracture is important b
ecause children with AHCD will need more extensive treatment than othe
rs, and their functional outcome seems to be worse.