Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis

Authors
Lall, N Meyer, JJM
Citation
N. Lall et Jjm. Meyer, Inhibition of drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis by diospyrin, isolated from Euclea natalensis, J ETHNOPHAR, 78(2-3), 2001, pp. 213-216
Citations number
31
Categorie Soggetti
Pharmacology & Toxicology
Journal title
JOURNAL OF ETHNOPHARMACOLOGY
ISSN journal
03788741 → ACNP
Volume
78
Issue
2-3
Year of publication
2001
Pages
213 - 216
Database
ISI
SICI code
0378-8741(200112)78:2-3<213:IODADS>2.0.ZU;2-X
Abstract
The binaphthoquinoid, diospyrin, was isolated from Euclea natalensis A.DC., and evaluated for its activity against drug-sensitive and drug-resistant s trains of Mycobacterium tuberculosis. The minimal inhibitory concentration (MIC) of diospyrin was found to be 100 mug/ml for all the M. tuberculosis s trains. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.