A six station ProSim (Manchester, UK) knee simulator was used to assess the
wear of six PFC (DePuy) fixed bearing total knee replacements under two di
fferent kinematic conditions defined as low and high kinematic inputs. The
high kinematics displacement and rotation inputs were based on the kinemati
cs of the natural knee with ISO standards used for the axial load and flexi
on. Low kinematics were defined as approximately half the magnitude. The si
x specimens were run for three million cycles under low kinematics and thre
e million cycles under high kinematics. The mean wear rate found during the
low kinematics phase was 7.7 +/- 2mm(3) per million cycles. This then incr
eased significantly to an average wear rate of 41 +/- 14mm(3) during the hi
gh kinematics input phase. The wear areas were characterized by a predomina
nt damage mode of burnishing with some abrasive wear occurring during the h
igh kinematics phase. This study supports the findings that introduction of
cross-shearing of the polyethylene by introducing both rotational and ante
rior/posterior displacement increases the wear rate. This has implications
for younger patients with higher levels of activity that need knee replacem
ents. (C) 2001 Kluwer Academic Publishers.