Tumoral calcinosis in hemodialysis patients: about three cases

Three patients (2 females, 1 male) with a mean age of 51,4 years receiving long term hemodialysis affected by tumoral calcinosis were analysed. Clinic al, radiological and pathological features were evaluated and pathogenic we re reviewed. The joints involved int the cases presented in this report wer e the hip shoulder and finger. The lesions were bilateral in shoulder. An i ncreased calcium-phosphorus product (Ca x P) was observed in all patients w ith secondary hyperparathyroidism in one case. Surgery was carried out in a ll patients. No relapse of the tumoral calcinosis was observed after surger y. The most important pathogenic factor involved in uremic tumoral calcinos is is an increase in calcium-phosphorus product (Ca x P) not necessarly rel ated to hyperparathyroidism. Therefore, maintaining the calcium x phosphate product within the normal range appears to be the most important factor it o prevent the appearance of uraemic tumoral calcinosis.