Rapid infusion of intravenous immune globulin in patients with neuromuscular disorders

The safety and efficiency of a novel method of rapid-infusion IV immunoglob ulin (IVIg) were retrospectively reviewed in 50 patients with neuromuscular disorders. There were 89 adverse events after 341 rapid infusions (26%), 3 .5% of which were considered to be major (requiring hospitalization) and 66 %, minor. All patients recovered without sequelae, and there were no deaths . Fourteen of 17 patients (82%) receiving maintenance therapy preferred rap id IVIg infusion because of its convenience. Rapid-infusion IVIg can be giv en safely and conveniently in many patients with neuromuscular disorders.