Background. In 1991 the Advisory Committee on Immunization Practices recomm
ended vaccination of all infants with three doses of hepatitis B virus vacc
ine (HepB) by 18 months of age as a key component of a comprehensive strate
gy to eliminate hepatitis B virus transmission in the United States. The Am
erican Academy of Pediatrics and the American Academy of Family Physicians
published similar recommendations soon afterward.
Methods. Data were obtained from the National Immunization Survey, a survey
that began in 1994 and is conducted quarterly by the Centers for Disease C
ontrol and Prevention to estimate vaccination coverage among noninstitution
alized US children 19 to 35 months of age.
Results. The 1999 National Immunization Survey data indicate that similar t
o 88.1% (95% confidence interval, 87.4, 88.8) of children 19 to 35 months o
f age had received at least three doses of HepB (HepB3). There has been a c
onsistent increase in HepB3 coverage since 1994. However, the rate of incre
ase has slowed in recent years and HepB3 coverage remains lower than covera
ge attained with three doses of diphtheria-tetanus-pertussis and Haemophilu
s influenzae vaccines. HepB3 coverage varied slightly by race/ethnicity and
was highest among white and Asian children (89%). Coverage also varied by
state; 26 states had levels of at least 90%.
Conclusions. Since the 1991 recommendations for universal hepatitis B vacci
nation, there has been a dramatic increase in coverage levels among childre
n 19 to 35 months of age. However, the Childhood Immunization Initiative go
al of 90% coverage has not been reached. Therefore continued efforts are ne
eded to protect US children against this serious but preventable infection.