Degeneracy and complexity in biological systems

Citation
Gm. Edelman et Ja. Gally, Degeneracy and complexity in biological systems, P NAS US, 98(24), 2001, pp. 13763-13768
Citations number
47
Categorie Soggetti
Multidisciplinary
Journal title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
ISSN journal
00278424 → ACNP
Volume
98
Issue
24
Year of publication
2001
Pages
13763 - 13768
Database
ISI
SICI code
0027-8424(20011120)98:24<13763:DACIBS>2.0.ZU;2-C
Abstract
Degeneracy, the ability of elements that are structurally different to perf orm the same function or yield the same output, is a well known characteris tic of the genetic code and immune systems. Here, we point out that degener acy is a ubiquitous biological property and argue that it is a feature of c omplexity at genetic, cellular, system, and population levels. Furthermore, it is both necessary for, and an inevitable outcome of, natural selection.