Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: Report of four cases

Authors
Junghans, U Seitz, RJ Wittsack, HJ Aulich, A Siebler, M
Citation
U. Junghans et al., Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein IIb/IIIa inhibitor: Report of four cases, RADIOLOGY, 221(3), 2001, pp. 795-801
Citations number
37
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Journal title
RADIOLOGY
ISSN journal
00338419 → ACNP
Volume
221
Issue
3
Year of publication
2001
Pages
795 - 801
Database
ISI
SICI code
0033-8419(200112)221:3<795:TOABAT>2.0.ZU;2-#
Abstract
In four patients with acute basilar artery thrombosis, complete arterial re canalization and good neurologic outcome were achieved with a treatment com bining alteplase with tirofiban. In no cases were cerebral or extracerebral hemorrhagic complications observed. Combined fibrinolytic agents and glyco protein IIb/IIIa inhibitors may have high potential in the treatment of acu te cerebrovascular thrombosis.