First-pass myocardial perfusion MR imaging with outer-volume suppression and the intravascular contrast agent NC1001150 injection: Preliminary results in eight patients

Citation
T. Bjerner et al., First-pass myocardial perfusion MR imaging with outer-volume suppression and the intravascular contrast agent NC1001150 injection: Preliminary results in eight patients, RADIOLOGY, 221(3), 2001, pp. 822-826
Citations number
11
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
Journal title
RADIOLOGY
ISSN journal
00338419 → ACNP
Volume
221
Issue
3
Year of publication
2001
Pages
822 - 826
Database
ISI
SICI code
0033-8419(200112)221:3<822:FMPMIW>2.0.ZU;2-E
Abstract
The authors evaluated the feasibility of combining single-shot T2-weighted turbo spin-echo magnetic resonance (MR) imaging and first-pass myocardial p erfusion MR imaging with an intravascular ultrasmall superparamagnetic iron oxide (USPIO) contrast agent, NC100150 Injection (3 mg of iron per kilogra m of body weight). Eight patients with coronary vessel disease underwent T2 -weighted turbo spin-echo MR imaging (inplane resolution, 1-2 mm) during th e first pass of the USPIO contrast agent. The mean decrease in signal inten sity in myocardium perfused by a nonstenotic coronary artery was 59% +/- 13 (SD) (P < .012) This method is feasible for imaging of myocardial perfusio n.