First-pass myocardial perfusion MR imaging with outer-volume suppression and the intravascular contrast agent NC1001150 injection: Preliminary results in eight patients
T. Bjerner et al., First-pass myocardial perfusion MR imaging with outer-volume suppression and the intravascular contrast agent NC1001150 injection: Preliminary results in eight patients, RADIOLOGY, 221(3), 2001, pp. 822-826
Citations number
11
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging","Medical Research Diagnosis & Treatment
The authors evaluated the feasibility of combining single-shot T2-weighted
turbo spin-echo magnetic resonance (MR) imaging and first-pass myocardial p
erfusion MR imaging with an intravascular ultrasmall superparamagnetic iron
oxide (USPIO) contrast agent, NC100150 Injection (3 mg of iron per kilogra
m of body weight). Eight patients with coronary vessel disease underwent T2
-weighted turbo spin-echo MR imaging (inplane resolution, 1-2 mm) during th
e first pass of the USPIO contrast agent. The mean decrease in signal inten
sity in myocardium perfused by a nonstenotic coronary artery was 59% +/- 13
(SD) (P < .012) This method is feasible for imaging of myocardial perfusio
n.