J. Tacke et al., Nephron-sparing percutaneous ablation of a 5 cm renal cell carcinoma by superselective embolization and percutaneous RF-ablation, ROFO-F RONT, 173(11), 2001, pp. 980-983
Citations number
15
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
Purpose: To report on the nephron-sparing, percutaneous ablation of a large
renal cell carcinoma by combined superselective embolization and percutane
ous radiofrequency ablation. Materials and Methods: A 5 cm renal cell carci
noma of a 43-year-old drug abusing male with serologically proven HIV, hepa
titis B and C infection, who refused surgery, was superselectively embolize
d using microspheres (size: 500-700 mum) and a platinum coil under local an
esthesia. Percutaneous radiofrequency ablation using a 7 F LeVeen probe (si
ze of expanded probe tip: 40 mm) and a 200 Watt generator was performed one
day after transcatheter embolization under general anesthesia. Results: Th
e combined treatment resulted in complete destruction of the tumor without
relevant damage of the surrounding healthy renal tissue. The patient was di
scharged 24 hours after RF ablation. No complications like urinary leaks or
fistulas were observed and follow up CT one day and 4 weeks after the radi
ofrequency intervention revealed no signs of residual tumor growth. Conclus
ion: The combined transcatheter embolization and percutaneous radiofrequenc
y ablation of renal cell carcinoma has proved technically feasible, effecti
ve, and safe in this patient. It may be offered as an alternative treatment
to partial or radical nephrectomy under certain circumstances. Abbreviatio
ns: RF=radiofrequency ablation; CT=computed tomography; HIV=human immunodef
iciency virus.