MALIGNANT EPITHELIAL SKIN TUMORS IN HERED ITARY HEMORRHAGIC TELANGIECTASIA (OSLER-WEBER-RENDU-SYNDROME)

A 65 year old male patient was diagnosed with hereditary hemorrhagic t elangiectasia at 30. During recent years he has suffered frequent, alm ost daily, nose bleeds causing anemia and making several blood transfu sions necessary. In the past 2-3 years,the patient has developed multi ple squamous cell carcinomas on the face. These un-unsually large tumo urs were treated by micrographic surgery using paraffin sections and t he defects closed with a variety of flaps and grafts. Several solar ke ratoses were also removed. If hemostasis parameters are normal, skin s urgery can be performed without hestitation in hereditary hemorrhagic telangiectasia.