Electronic tuning in C-1-symmetric chelating diphosphane ligands supportedon stereogenic aryl-heteroaryl templates

The syntheses of a wide range of novel C-1-symmetric chelating diphosphanes with stereogenic axes are reported. These ligands feature identical or dif ferent phosphanyl groups supported on diverse atropisomeric templates based on the interconnection of five-membered heteroaromatic and six-membered ca rbocyclic rings, Easy synthetic accessibility, independent tunability of th e electronic and steric properties of the two phosphane donors, the low cos t and the good stereoselection ability of some of them obtained in an enant iopure state are the main advantageous features of this class of ligands.