Integrated optical and microoptical detection schemes are advantageous for
the detection of surface-bound biochemical reactions. Fluorescence detectio
n in combination with miniaturised multiple reflection elements is very sen
sitive due to the effective excitation of fluorescence. These methods are e
asily realised in a chip format, which is very promising e.g. for DNA analy
sis. Beside this, label free detection is possible, based on waveguide opti
cs. A very sensitive interferometric system is presented.