Patagonicoside A: a novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus

Authors
Murray, AP Muniain, C Seldes, AM Maier, MS
Citation
Ap. Murray et al., Patagonicoside A: a novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus, TETRAHEDRON, 57(47), 2001, pp. 9563-9568
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
47
Year of publication
2001
Pages
9563 - 9568
Database
ISI
SICI code
0040-4020(20011119)57:47<9563:PAANAD>2.0.ZU;2-H
Abstract
A new triterpene glycoside, patagonicoside A (1), has been isolated from th e sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (H-1-, C-13-, H-1-H-1 COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide w ith a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifu ngal activity against the pathogenic fungus Cladosporium cucumerinum. (C) 2 001 Elsevier Science Ltd. All rights reserved.