A concise synthesis of L-4,4-difluoroglutamine

Authors
Meffre, P Dave, RH Leroy, J Badet, B
Citation
P. Meffre et al., A concise synthesis of L-4,4-difluoroglutamine, TETRAHEDR L, 42(49), 2001, pp. 8625-8627
Citations number
22
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
49
Year of publication
2001
Pages
8625 - 8627
Database
ISI
SICI code
0040-4039(200112)42:49<8625:ACSOL>2.0.ZU;2-E
Abstract
L-4,4-Difluoroglutamine 1 of high optical purity was prepared from (R)-Garn er's aldehyde 2 using Reformatsky reaction as the key step for introducing the fluorinated side-chain. (C) 2001 Elsevier Science Ltd. All rights reser ved.