Potential hazard of simultaneous occurrence of aflatoxin B-1 and ochratoxin A

Citation
M. Sedmikova et al., Potential hazard of simultaneous occurrence of aflatoxin B-1 and ochratoxin A, VET MED-CZ, 46(6), 2001, pp. 169-174
Citations number
31
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
VETERINARNI MEDICINA
ISSN journal
03758427 → ACNP
Volume
46
Issue
6
Year of publication
2001
Pages
169 - 174
Database
ISI
SICI code
0375-8427(200106)46:6<169:PHOSOO>2.0.ZU;2-8
Abstract
Contents of aflatoxin B-1 (AFB(1)) and ochratoxin A (OA) in the samples of wheat and barley were detected by RIA method. Average contents of AFB(1) in the samples of wheat and barley were 2.4 mug/kg and 2.2 mug/kg, respective ly. Average contents of OA in the samples of wheat and barley were 3.1 mug/ kg and 2.4 mug/kg, respectively. The contents of mycotoxins corresponded to the allowed limits in food. During the studies of mutagenic activity of my cotoxins and their combinations by means of Ames test it was found that OA could increase the mutagenicity of AFB(1) in the case of their simultaneous occurrence in the same substrate.