E. Otsuji et al., Is timing of death from tumor recurrence predictable after curative resection for gastric cancer?, WORLD J SUR, 25(11), 2001, pp. 1373-1376
It is still difficult to predict whether cancer in patients who undergo cur
ative gastrectomy for gastric cancer will recur and when they will die of r
ecurrence. This study clarified predictive factors related to timing of dea
th from tumor recurrence. A multivariate analysis was used to assess the de
pendence of death on postoperative tumor recurrence and the dependence of t
he timing of death on tumor recurrence. Patients were divided into two grou
ps according to the timing of death: those who died of tumor recurrence les
s than 2 years after surgery and those who died more than 2 years after sur
gery. Depth of cancer invasion, regional lymph node metastasis, and tumor s
ize were independently correlated with tumor recurrence after curative gast
rectomy. Only the depth of cancer invasion independently correlated with th
e timing of death due to tumor recurrence. It might be possible to predict
the timing of death from tumor recurrence by the depth of cancer invasion i
nto the gastric wall.