Cardiac abnormalities detected by Doppler imaging in patients with neurofibromatosis type 1

Authors
Tedesco, MA Di Salvo, G Natale, F Caputo, S Calabrese, E Grassia, C Ratti, G Iarussi, D Iacono, A Lama, G
Citation
Ma. Tedesco et al., Cardiac abnormalities detected by Doppler imaging in patients with neurofibromatosis type 1, AM J CARD, 88(10), 2001, pp. 1198
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
88
Issue
10
Year of publication
2001
Database
ISI
SICI code
0002-9149(20011115)88:10<1198:CADBDI>2.0.ZU;2-F
Abstract
To analyze myocardial compliance in young patients with neurofibromatosis t ype I without cardiovascular malformations compared with normal subjects, w e used pulsed Doppler tissue imaging to study 42 patients at our pediatric department (mean age 10 years, range 4 to 19). Our study is the first to de monstrate the presence of a diastolic dysfuntion in patients with neurofibr omatosis type I and to suggest the presence of an underlying cardiovascular disease in these patients.