Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus

Authors
Abbasi, F Asagmi, T Cooke, JP Lamendola, C McLaughlin, T Reaven, GM Stuehlinger, M Tsao, PS
Citation
F. Abbasi et al., Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus, AM J CARD, 88(10), 2001, pp. 1201
Citations number
19
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
88
Issue
10
Year of publication
2001
Database
ISI
SICI code
0002-9149(20011115)88:10<1201:PCOADA>2.0.ZU;2-8
Abstract
Increased risk of coronary heart disease in patients with type 2 diabetes c annot be accounted for by differences in conventional risk factors. This st udy demonstrates that plasma concentrations of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, are increased in patient s with type 2 diabetes, thereby identifying a new and potentially important coronary heart disease risk factor in this patient population.