Despite their widespread utilization, little is known about the quality of
pathologists' assistants' services. Pathologists' assistants' performance w
as compared with pathology residents' performance using the metrics of lymp
h node retrieval and tissue resubmission rates. Lymph node retrieval was ca
lculated by retrospective review of surgical pathology reports from a sampl
e of axillary dissection, mastectomy, and colorectal specimens. Tissue resu
bmission rates were calculated by retrospective review of a sample of gener
al surgical pathology reports. Pathologists' assistants retrieved a signifi
cantly greater total number of lymph nodes compared with pathology resident
s; however, there was no difference in the total number of positive lymph n
odes retrieved. Cases for which pathologists' assistants performed the gros
s examination had a significantly decreased resubmission rate compared with
those performed by residents. In this setting, the gross examination perfo
rmance of pathologists' assistants was equivalent to or superior to that of
pathology residents. These results provide the first information available
relating to pathologists' assistants' performance in surgical pathology.