Increasing age is a major risk factor for developing cancer and the number
of older people is rapidly expanding. Therefore, cancer in the geriatric po
pulation is becoming an emerging problem.
Older patients are extremely heterogeneous. Instruments collecting informat
ion related to comorbidity and disability, (which have both been demonstrat
ed to affect the survival of elderly patients) may help treatment decision.
The G.I.O.Ger (Gruppo Italiano di Oncologia Geriatrica) has validated a Com
prehensive Geriatric Assessment (CGA) scale for geriatric cancer patients,
and we recommend its use in clinical practice. Our findings suggest that ca
ncer adversely affects physical performance and psychological status less t
han other comorbidities. Many aspects of physical limitations are not total
ly recognised by performance status, in particular those aspects of daily l
ife that require instrumental activities and that may affect adherence to d
iagnostic or therapeutic protocols.
Quality of life as a main objective in the management of elderly cancer pat
ients is now recognized by many clinicians.
In clinical practice, quality of life means maintenance of function and sym
ptom control, and quality-of-life instruments rated by the patient rather t
han by clinicians should be preferred. Whether it is preferable to use canc
er-specific or generic instruments is an ongoing debate.