Remission of severe, intractable autoimmune haemolytic anaemia following matched unrelated donor transplantation

Immune-mediated haemolytic anaemia presenting post allogeneic bone marrow t ransplantation is often alloimmune in origin due to ABO or minor red cell i ncompatibilities. Autoimmune haemolytic anaemia is also recognised, is freq uently difficult to treat and overall prognosis is often poor, usually from associated problems. Here, we present a case report of autoimmune haemolys is presenting in an 8-year-old boy 6 months post allogeneic bone marrow tra nsplant requiring 4 years of immunosuppressive therapy before remission of haemolysis. This case report highlights the fact that it is possible for ha emolysis to resolve post transplant even after years of immunosuppressive t herapy.