Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

Authors
Kenyon, AP Piercy, CN Girling, J Williamson, C Tribe, RM Shennan, AH
Citation
Ap. Kenyon et al., Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis, BR J OBST G, 108(11), 2001, pp. 1190-1192
Citations number
7
Categorie Soggetti
Reproductive Medicine","da verificare
Journal title
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
ISSN journal
14700328 → ACNP
Volume
108
Issue
11
Year of publication
2001
Pages
1190 - 1192
Database
ISI
SICI code
1470-0328(200111)108:11<1190:PMPALF>2.0.ZU;2-8
Abstract
Obstetric cholestasis is a liver disorder unique to pregnancy, which typica lly presents with pruritus. However, pruritus is common in pregnancy and th e diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any, abnorm ality in liver function tests (including total serum bile acids) and discus s the implications or this for clinical practice.