Features of childhood sexual abuse and the development of psychiatric and substance use disorders

Background Childhood sexual abuse (CSA) is associated with an increased ris k of subsequent psychiatric disorders. Aims To explore the risk associated with features of CSA and examine whethe r specific associations exist between particular profiles of CSA and the de velopment of specific syndromes. Method In a population-based sample of adult female twins, we used logistic regression to explore the association between features of CSA (reported by the twin and her co-twin) and lifetime major depression, generalised anxie ty disorder, bulimia nervosa, panic disorder and alcohol and drug dependenc e. Results In univariate and stepwise multiple regressions, patterns of predic tors differed, although not significantly, across diagnoses. Greater risk w as associated with attempted or completed intercourse, the use of force or threats, abuse by a relative, and a negative response by someone who was to ld about the abuse. Similar patterns were observed with. co-twin reports. Conclusions Specific features of CSA differentially increase risk of later psychopathology; however, there do not appear to be unique predictive relat ionships between features of CSA and the emergence of specific psychiatric disorders. Declaration of interest None. Funding detailed in Acknowledgements.