A randomized trial comparing the hand-mounted JoStent with the premounted Multi-Link Duet stent in patients with coronary artery disease

The objective of this multicenter randomized study was to compare the angio graphic and clinical results achieved 1 year after coronary placement of tw o stent models: the hand-mounted JoStent and the premounted Multi-Link Duet stent. We included 506 patients who were randomly assigned to receive eith er the hand-mounted JoStent (n = 252) or the premounted Multi-Link Duet ste nt (n = 253). The primary endpoint of the study, late lumen loss, measured 1.12 mm in the JoStent group and 1.17 mm in the Multi-Link Duet group. Thes e values were statistically equivalent (P = 0.02 from the equivalence test) . No significant difference was observed in the incidence of restenosis, 24 .2% in the JoStent and 25.2% in the Multi-Link Duet stent group, and target vessel revascularization, 13.9% in the JoStent and 15.4% in the Multi-Link Duet patients. In conclusion, the hand-mounted JoStent and the premounted Multi-Link Duet stent enable excellent procedural success rates and equally favorable 1-year angiographic and clinical outcomes. (C) 2001 Wiley-Liss, Inc.