Percutaneous interventional procedures in the renal arteries are usually pe
rformed using a femoral or brachial vascular access. The transradial approa
ch, which has been extensively investigated for coronary angiography and in
tervention, could be an attractive new technique for renal artery angioplas
ty and stenting. In 18 patients with hemodynamically relevant unilateral re
nal artery stenosis (mean diameter stenosis, 83% +/- 18%; right, n = 7; lef
t, n = 11), interventional treatment with PTA and stenting was performed us
ing a left (n = 16) or right (n = 2) radial artery access. Indications for
the transradial approach were acute aorto-renal angles or severe peripheral
arterial obstructions. After engagement of the renal artery ostium with a
6 Fr Multipurpose guiding catheter (length, 125 cm; Cordis) the stenosis wa
s passed with a 0.014" guidewire followed by stent implantation (ACS Multi-
Link RX Ultra, Guidant; length, 18 mm; diameter, 5 mm). Direct stenting was
successfully performed in 16 cases. Predilatations were required in two ca
ses. In five patients, optimal stent expansion was achieved by additional p
ostdilatations. A primary technical success (residual stenosis < 30%) could
be achieved in all cases. There were no periprocedural complications. Acco
rding to color-coded doppler ultrasound, all access site arteries showed a
normal perfusion. Clinically blood pressure control was improved in 11 pati
ents with a significant reduction in systolic and diastolic blood pressure
values. Serum creatinine values dropped from 1.81 +/- 0.3 mg/di to 1.49 +/-
0.3 mg/dl (P < 0.001). Transradial renal artery angioplasty and stenting i
s technically feasible and safe. Particularly in patients with unfavorable
vessel anatomy, this new cranio-caudal approach is an attractive alternativ
e technique. (C) 2001 Wiley-Liss, Inc.