Synthesis and DNA-binding properties of dinuclear platinum( II)-amine complexes of 1,7-dicarba-closo-dodecaborane(12)

Authors
Woodhouse, SL Rendina, LM
Citation
Sl. Woodhouse et Lm. Rendina, Synthesis and DNA-binding properties of dinuclear platinum( II)-amine complexes of 1,7-dicarba-closo-dodecaborane(12), CHEM COMMUN, (23), 2001, pp. 2464-2465
Citations number
31
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
23
Year of publication
2001
Pages
2464 - 2465
Database
ISI
SICI code
1359-7345(2001):23<2464:SADPOD>2.0.ZU;2-J
Abstract
The first examples of platinum(II)-amine complexes containing a dicarba-clo so-dodecaborane(12) (carborane) moiety are described; preliminary in vitro DNA-binding experiments indicate that the complexes are capable of targetti ng plasmid DNA.