TRICARBONYL(ETA(6) ARENE)CHROMIUM(0) COMPLEXES AS CHIRAL AUXILIARIES - HOMOCHIRAL-BETA-LACTAMS SYNTHESIS VIA [2+2] CYCLOADDITION REACTION

Authors
BALDOLI C DELBUTTERO P LICANDRO E MAIORANA S PAPAGNI A
Citation
C. Baldoli et al., TRICARBONYL(ETA(6) ARENE)CHROMIUM(0) COMPLEXES AS CHIRAL AUXILIARIES - HOMOCHIRAL-BETA-LACTAMS SYNTHESIS VIA [2+2] CYCLOADDITION REACTION, Tetrahedron : asymmetry, 5(5), 1994, pp. 809-812
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
5
Issue
5
Year of publication
1994
Pages
809 - 812
Database
ISI
SICI code
0957-4166(1994)5:5<809:TACACA>2.0.ZU;2-E
Abstract
A highly enantioselective synthesis of beta-lactams ''via'' a [2+2] cy cloaddition reaction of homochiral tricarbonyl [N-(2-methoxybenzyliden e)aniline]chromium with ketenes is reported. Moreover the reaction of (+)-(IS)-tricarbonyl[4-methoxy-N-(2-methoxy cinnamylidene)aniline]chro mium with acetoxy ketene gives the corresponding 4-styryl-beta-lactam in good yield but with moderate stereoselection.