J. Korner et al., Perioperative local instillation of ropivacaine for postoperative pain relief after surgery on extremities, CHIRURG, 72(11), 2001, pp. 1353-1359
Introduction: The relief of postoperative pain remains one of the most impo
rtant goals for adequate surgical patient care. Methods: Prospective, rando
mised, double-blinded study, including 118 patients (67 M;/ 51 F; median ag
e 43 years, min. 18, max. 74). Two groups were formed. In the verum group a
wound instillation with ropivacaine was performed, in the control group no
t. Intensity of pain, demand for analgesics and satisfaction of the patient
were evaluated postoperatively. In 10 patients ropivacaine plasma levels w
ere measured. Results: Significant postoperative pain relief and a decrease
in analgesic consumption were found on instillation of ropivacaine. Compar
ed to the control group, patients receiving ropivacaine were significantly
more satisfied with the postoperative pain management. Potential toxic plas
ma levels were not found. Conclusion: By the presented method, the surgeon
actively contributes to a significant reduction in postoperative pain and a
nalgesic consumption. Furthermore, the patient's benefit is reflected by hi
gher satisfaction with the pain management. Complications due to toxic plas
ma levels are not seen.