B. Saric et al., Brachytherapy - Optional treatment for choroidal neovascularization secondary to age-related macular degeneration, COLL ANTROP, 25, 2001, pp. 89-96
Age-related macular degeneration (ARMD) presents the main cause of irrevers
ible loss of central vision in older population, due to a progressive neuro
retinal damage and damage of retinal pigment epithelium of foveal area. Thi
s observation emphasizes the insufficiency of all presently used therapeuti
c procedures. Therefore, investigation has been conducted at the University
Eye Clinic Zagreb for the last three years testing the effects of brachyth
erapy with direct episcleral application of ruthenium applicators to the po
sterior pole of the globe. Forty-two patients aged 58-79 were followed for
a min. of 12 months. During this period their central visual acuities remai
ned stable. Six patients showed one-line improvement of visual acuity and 8
patients showed no changes. Twenty-one patient lost 1-2 lines of visual ac
uity and 7 patients lost more than 2 lines. According to this we can conclu
de that patients treated with brachytherapy showed significantly better res
ults compared to the control subjects, which is very encouraging.