The aim of this prospective clinical study was to investigate the intraocul
ar pressure (IOP) reduction after selective laser trabeculoplasty (SLT) in
patients with primary open-angle glaucoma (POAG), SLT represents a new meth
od in the treatment of POAG. Fifty eyes with uncontrolled POAG were treated
with a frequency doubled, Q-switched Nd:YAG laser (532 nm), The pattern of
treatment was applying approximately 50 burns to 180 degrees of the trabec
ular meshwork at energy levels ranging from 0.40-0.92 mJ per pulse. After S
LT eyes were maintained with the identical hypotensive medical therapy as t
hat before treatment. IOP was measured before treatment, I and 7 days after
treatment and 1, 3, 6 and 12 months after treatment. The mean pretreatment
IOP was 22.48 (SD 1.84) mm Hg. At the end of I month follow-up period the
mean reduction of IOP was 4.86 (SD 2.38) mmHg or 21.6%; after 3 months the
mean reduction was 5.66 (SD 2.40) mmHg or 25.2%; after 6 months the mean re
duction of IOP was 5.06 (SD 2.37) mmHg or 22.5%; at the end of 12 months fo
llow-up period the mean reduction was 4.92 (SD 2.58) mmHg or 21.9%. It can
be concluded that SLT presents a new and effective method of IOP reduction
in the treatment of POAG.