An integrated genetic and physical map of the 650-kb region containing thecongenital polycystic kidney (cpk) locus on mouse Chromosome 12

Authors
Mrug, M Green, WJ DasGupta, S Beier, DR Lu, W D'Eustachio, P Guay-Woodford, LM
Citation
M. Mrug et al., An integrated genetic and physical map of the 650-kb region containing thecongenital polycystic kidney (cpk) locus on mouse Chromosome 12, CYTOG C GEN, 94(1-2), 2001, pp. 55-61
Citations number
31
Categorie Soggetti
Molecular Biology & Genetics
Journal title
CYTOGENETICS AND CELL GENETICS
ISSN journal
03010171 → ACNP
Volume
94
Issue
1-2
Year of publication
2001
Pages
55 - 61
Database
ISI
SICI code
0301-0171(2001)94:1-2<55:AIGAPM>2.0.ZU;2-B
Abstract
Mice homozygous for the congenital polycystic kidney (cpk) mutation develop a rapidly progressive form of polycystic kidney disease. We report an inte grated genetic and physical map of the 650-kb region containing the cpk loc us and the exclusion of Rrm2 and Idb2 as candidate cpk genes. Our study est ablishes the requisite foundation for positional cloning of the cpk gene. C opyright (C) 2001 S. Karger AG, Basel.