Observations on a new collagen barrier membrane in 16 consecutively treated patients. Clinical and histological findings

Background: Space-maintaining capacity, cell disclusive potential, and stab ility over time are crucial factors to achieving sufficient bone augmentati on with membrane barriers. The case series presented here assessed a new co llagen barrier used in bone augmentation. Clinically, the healing pattern, especially in cases of secondary healing, was studied. Methods: Soft tissue healing was documented by photographs, and the size of the dehiscences calculated by image analysis. The measurements were perfor med on digitized photographs. During reentry, barrier remnants were dissect ed and histologically evaluated. Results: The mean value for dehiscences was 35.5 mm(2); all dehiscences hea ted within 4 weeks after the exposure became evident. The difference was st atistically significant between the week 2 and week 6 visits (P = 0.008) fo r each previously exposed site. The histologic observation of barrier remna nts revealed direct apposition of fibrous and bone tissues on the membrane surface. Conclusion: In cases of membrane exposure, gingival dehiscences always disa ppeared in the following weeks without affecting the healing process. Histo logic results showed barrier stability over a 6-month period, promoting bon e regeneration.