Synthesis of (-)-ent-altholactone, (+)-7a-epi-altholactone, (-)-ent-isoaltholactone and (-)-7a-epi-Isoaltholactone from 2,3-O-cyclohexylidene-D-glyceraldehyde

Authors
Hiratate, A Kiyota, H Oritani, T
Citation
A. Hiratate et al., Synthesis of (-)-ent-altholactone, (+)-7a-epi-altholactone, (-)-ent-isoaltholactone and (-)-7a-epi-Isoaltholactone from 2,3-O-cyclohexylidene-D-glyceraldehyde, J PESTIC S, 26(4), 2001, pp. 361-365
Citations number
15
Categorie Soggetti
Entomology/Pest Control
Journal title
JOURNAL OF PESTICIDE SCIENCE
ISSN journal
03851559 → ACNP
Volume
26
Issue
4
Year of publication
2001
Pages
361 - 365
Database
ISI
SICI code
0385-1559(2001)26:4<361:SO(((>2.0.ZU;2-8
Abstract
Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3 a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyc eraldehyde via twice separation of diastereomers.