Synthesis and characterization of polyisocyanides derived from alanine andglycine dipeptides

Authors
Cornelissen, JJLM Graswinckel, WS Adams, PJHM Nachtegaal, GH Kentgens, APM Sommerdijk, NAJM Nolte, RJM
Citation
Jjlm. Cornelissen et al., Synthesis and characterization of polyisocyanides derived from alanine andglycine dipeptides, J POL SC PC, 39(24), 2001, pp. 4255-4264
Citations number
23
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
ISSN journal
0887624X → ACNP
Volume
39
Issue
24
Year of publication
2001
Pages
4255 - 4264
Database
ISI
SICI code
0887-624X(200112)39:24<4255:SACOPD>2.0.ZU;2-V
Abstract
The synthesis and characterization of polymers derived from isocyanopeptide s are described. Optically pure dipeptides based on alanine and glycine wer e equipped with an isocyano function and subsequently polymerized with a Ni (II) catalyst. Infrared and NMR spectroscopy indicated that the side chains of the polymers were connected by well-defined arrays of intramolecular hy drogen bonds. The weight-average molecular weights of the polymers were det ermined by atomic force microscopy to be 200-400 kg/mol (polydispersity ind ex = 1.4-1.7). (C) 2001 John Wiley & Sons, Inc.