Intralesional injection for hepatic metastasis from cervical carcinoma - Areport of two cases

Background: The treatment of isolated hepatic metastasis from carcinoma of the uterine cervix has yet to be established. We tested the efficacy of per cutaneous injection of ethanol and acetic acid as a curative-intent treatme nt modality for this rare event. Cases: under real-time sonographic guidance, two patients with a solitary h epatic metastasis from carcinoma of the cervix were treated with 99.5% perc utaneous ethonal injection (one patient) and 50% percutaneous acetic acid i njection (the other patient). The treatment was repeated weekly if laborato ry data permitted and aspiration cytology interpreted on site showed tumor cells. Cytology after complete treatment showed no residual tumor cells in either case. Both patients had no evidence of disease during follow-up for 12 and 24 months, respectively. Conclusion:Treatment was successful in two patients with isolated hepatic m etastastic lesion from carcinoma of the cervix who received percutaneous in jection of 99.5% ethanol or 50% acetic acid.