OCULAR GENE-THERAPY - THE BASIC SCIENCE AND CURRENT STATE OF RESEARCH

Citation
L. Dacruz et al., OCULAR GENE-THERAPY - THE BASIC SCIENCE AND CURRENT STATE OF RESEARCH, Australian and New Zealand journal of ophthalmology, 25(2), 1997, pp. 97-104
Citations number
45
Categorie Soggetti
Ophthalmology
ISSN journal
08149763
Volume
25
Issue
2
Year of publication
1997
Pages
97 - 104
Database
ISI
SICI code
0814-9763(1997)25:2<97:OG-TBS>2.0.ZU;2-H
Abstract
Recent technical advances have led to the demonstration of the molecul ar basis of many genetic eye diseases. Methods now in use have been ab le to both suppress and insert genes in vitro and in vivo in ocular ce lls. The combination of this new knowledge and these techniques offers the potential for a new therapeutic approach to diseases that current ly have no treatments. The scientific basis of gene therapy is introdu ced and then the current state oi research is discussed in relation to the eye and ocular tissues.